Abstract
Background
Pulmonary hypertension (PH) and portopulmonary hypertension (POPH) can be limitations
towards listing for liver transplantation (LT). Our study evaluates the correlation
of right ventricular systolic pressure (RVSP) and mean pulmonary artery pressure (mPAP)
on transthoracic echocardiogram (TTE) compared to mPAP on right heart catheterization
(RHC).
Methods
We performed a retrospective review of 723 patients who underwent LT evaluation at
our institution between 2012 and 2020. Our cohort consisted of patients with RVSP
and mPAP measured on TTE. A Wald t-test and area under the curve analysis were used
for statistical analyses.
Results
Patients with higher mPAP values on TTE (N=33) did not correlate with mPAP ≥ 35 mmHg
on RHC, while patients with higher RVSP values (N=147) on TTE were associated with
mPAP ≥ 35 mmHg on RHC. The cutoff value of RVSP ≥ 48 mmHg on TTE was associated with
mPAP ≥ 35 mmHg on RHC.
Conclusions
Our data suggest that RVSP compared to mPAP on TTE is a better indicator for mPAP
≥ 35 mmHg on RHC. RVSP can be used as a marker on echocardiography for identifying
patients with a higher likelihood of PH being a barrier to LT listing.
Key Indexing Terms
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Article info
Publication history
Published online: March 15, 2023
Accepted:
March 9,
2023
Received:
July 17,
2022
Publication stage
In Press Journal Pre-ProofIdentification
Copyright
© 2023 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved.
