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Intrathoracic extramedullary hematopoiesis

Published:February 21, 2023DOI:
      A 59-year-old male who had been diagnosed with small cell hypochromic anemia caused by iron deficiency, presented to thoracic clinic with chest pain. Thirty years ago, he had underwent colectomy for intestinal obstruction and worked in plateau area. Physical examination was normal. Laboratory data included mean white blood cell count of 10.10x109 per litre (reference range, 3.5 to 9.5), mean reticulocyte count of 0.1022x1012 per litre (reference range, 0.024 to 0.084), mean platelet count of 75 x109 per litre (reference range, 125 to 350), mean corpuscular volume of 74.40 femtoliters (reference range, 82 to 100), mean corpuscular hemoglobin of 23.30 peta-grams (reference range, 27 to 34), mean corpuscular hemoglobin concentration of 313 grams per limiter (reference range, 316 to 354). Abdominal ultrasound showed splenomegaly. Non-contrast chest CT found bilateral, broad base, posterior mediastinal mass (Fig. 1A). Magnetic resonance imaging revealed two equal, enhancement parenchymal, paravertebral masses, without adjacent bone or intervertebral foramen invasion (Fig. 1B). Pathological examination confirmed as extramedullary hematopoiesis by thoracoscopic biopsy (Fig. 1C). The patient was followed up in the hematology clinic postoperatively.
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