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Patient-Centered Focused Review| Volume 365, ISSUE 5, P457-461, May 2023

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Portal vein thrombosis as the presenting manifestation of JAK2 positive myeloproliferative neoplasm

Published:January 09, 2023DOI:https://doi.org/10.1016/j.amjms.2023.01.002

      Abstract

      Deep venous thrombosis (DVT) is a complication of myeloproliferative neoplasms (MPNs). However, DVTs in unusual sites such as portal vein thrombosis (PVT) are rare and may be the first clinical manifestation of occult MPNs. There is a need for increasing awareness of such manifestations; so, here we discuss a patient who presented with new portal vein thrombosis, underwent further studies, was ultimately diagnosed with JAK2 positive MPN, and started on appropriate treatment with improvement of thrombosis and controlled hematocrit.

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