A 28-year-old woman presented with pain and a mass in the abdomen for three months.
The mass was was diagnosed as a mixed germ cell tumour (grade 3 immature teratoma
and yolk sac tumour - FIGO stage IIIC). She underwent cytoreductive surgery, and three
months later, she presented with a recurrent abdominal lump. Contrast-enhanced computed
tomography (CECT) scan showed multiple deposits in the peritoneum, the largest measuring
23 × 17 × 12cm (Fig. 1A) and elevated tumour markers (Alpha Feto Protein (AFP): 3080ng/ml). She received
two lines of chemotherapy [Bleomycin, Etoposide and Cisplatin (BEP) and Vinblastine,
Ifosfamide & Cisplatin (VeIP)]. Post-chemotherapy, the patient's symptoms worsened
with increasing abdominal distension. CECT scan showed an increase in the size of
the lesion (Fig. 1B). However, the tumour markers were normal (AFP 8.34 ng/ml). She underwent a second-look
laparotomy with complete cytoreduction. Pathology revealed only elements of mature
teratoma with elements of all three germ cell layers (respiratory epithelium, mucinous
glands, cartilage and mature glial tissue forming nodules in the peritoneum) (Fig. 2A-D).
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to The American Journal of the Medical SciencesAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
Article info
Publication history
Published online: November 04, 2022
Accepted:
November 1,
2022
Received:
August 15,
2020
Identification
Copyright
© 2022 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved.
