A 49-year-old woman presented with a month history of right wrist drop and thumb numbness.
Electromyography/evoked potential examination indicated neurogenic damage of the right
radial nerve at the spiral groove of the humerus. During exploration of the radial
nerve, a tumor of 3 cm in length was attached to the nerve on the level of upper deltoid
ending point (Fig. 1A). The tumor was hard, with complete capsule. The tumor was separated from the nerve
and excised completely. Pathological examination indicated metastatic poorly differentiated
adenocarcinoma (Fig. 1B), with the following immunohistochemistry results: CK (+) (Fig. 1C), CK7 (+) (Fig. 1D), CK18 (+) (Fig. 1E), Vimentin (+), CK20 (-), TTF-1 (-), HMB45 (-). Subsequent chest computed tomography
demonstrated a lobulated nodular soft tissue density in the left upper lobe adjacent
to the pleura (Fig. 1F). The patient died 1 year after diagnosis of lung cancer.
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References
- A series of 146 peripheral non-neural sheath nerve tumors: 30-year experience at Louisiana State University Health Sciences Center.J Neurosurg. 2005; 102: 256-266
- A series of 397 peripheral neural sheath tumors: 30-year experience at Louisiana State University Health Sciences Center.J Neurosurg. 2005; 102: 246-255
Article info
Publication history
Published online: September 23, 2022
Accepted:
September 19,
2022
Received:
December 19,
2021
Publication stage
In Press Journal Pre-ProofIdentification
Copyright
© 2022 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved.
