Online Images in the Medical Sciences| Volume 365, ISSUE 3, e31-e32, March 2023

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Bronchiolitis of immune checkpoint inhibitor therapy-related pneumonitis

Published:September 22, 2022DOI:
      A 77-year-old man was diagnosed with lung adenocarcinoma and presented with bone and liver metastases (cT1bN2M1c; stage IVB). The driver mutations were negative, and the programmed cell death ligand 1 tumor proportion score was 80%. He underwent immune-checkpoint inhibitor (ICI) therapy (pembrolizumab 200 mg/m2) every three weeks. Pembrolizumab immunotherapy was administered for a total of 35 cycles, all lung lesions disappeared (Fig. 1A), and the therapeutic outcome was considered a complete response.
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        • Naidoo J.
        • Wang X.
        • Woo K.M.
        • et al.
        Pneumonitis in patients treated with anti-programmed death-1/programmed death ligand 1 therapy.
        J Clin Oncol. 2017; 35: 709-717
        • Delaunay M.
        • Cadranel J.
        • Lusque A.
        • et al.
        Immune-checkpoint inhibitors associated with interstitial lung disease in cancer patients.
        Eur Respir J. 2017; 501700050