Advertisement
Patient-Centered Focused Review| Volume 365, ISSUE 1, P99-103, January 2023

Malignant peritoneal mesothelioma

  • Cai-Pu Chun
    Affiliations
    Department of Pathology and Medical Research Center, Beijing Chaoyang Hospital, Capital Medical University, Chaoyang District, Beijing, PR China

    Department of Pathology, The Fourth Affiliated Hospital of Shihezi University, Akesu, Xinjiang, PR China.
    Search for articles by this author
  • Lin-Xie Song
    Affiliations
    Department of Pathology and Medical Research Center, Beijing Chaoyang Hospital, Capital Medical University, Chaoyang District, Beijing, PR China
    Search for articles by this author
  • Hong-Pan Zhang
    Affiliations
    Department of Pathology and Medical Research Center, Beijing Chaoyang Hospital, Capital Medical University, Chaoyang District, Beijing, PR China
    Search for articles by this author
  • Dan-Dan Guo
    Affiliations
    Department of Pathology and Medical Research Center, Beijing Chaoyang Hospital, Capital Medical University, Chaoyang District, Beijing, PR China
    Search for articles by this author
  • Gui-Xuan Xu
    Affiliations
    Department of Pathology and Medical Research Center, Beijing Chaoyang Hospital, Capital Medical University, Chaoyang District, Beijing, PR China
    Search for articles by this author
  • Ya Li
    Affiliations
    Department of Pathology and Medical Research Center, Beijing Chaoyang Hospital, Capital Medical University, Chaoyang District, Beijing, PR China
    Search for articles by this author
  • Xin Xin
    Affiliations
    Department of Pathology and Medical Research Center, Beijing Chaoyang Hospital, Capital Medical University, Chaoyang District, Beijing, PR China
    Search for articles by this author
  • Jiachen Cao
    Affiliations
    Department of Pathology and Medical Research Center, Beijing Chaoyang Hospital, Capital Medical University, Chaoyang District, Beijing, PR China
    Search for articles by this author
  • Feng Li
    Correspondence
    Corresponding author. Feng Li, MD, Department of Pathology and Medical Research Center, Beijing Chaoyang Hospital, Capital Medical University, No.8 Gongti South Road, Chaoyang District, Beijing 100020, PR China
    Affiliations
    Department of Pathology and Medical Research Center, Beijing Chaoyang Hospital, Capital Medical University, Chaoyang District, Beijing, PR China
    Search for articles by this author
Published:August 05, 2022DOI:https://doi.org/10.1016/j.amjms.2022.07.008
Malignant peritoneal mesothelioma
Previous ArticleSevere eosinophilic granulomatosis with polyangiitis responding to a combination of rituximab and mepolizumab
Next ArticleBilateral adrenal hemorrhage: A rare presentation of catastrophic anti-phospholipid syndrome

      Abstract

      Malignant peritoneal mesothelioma (MPM) is a rare, life-threatening malignant tumor. We present a report of a rare case of a 67-year-old male patient with MPM and severe abdominal pain, bloating, and bloody ascites as manifestations. The diagnosis was confirmed by cytology of ascites aspiration fluid and further verified by laparoscopic exploratory biopsy. The characteristics of signs and clinical manifestations in this case are less common. As everyone knows, asbestos exposure is usually associated with pleural mesothelioma, but only 6%–10% of malignant mesothelioma cases originate from the peritoneum, which is far less than pleural mesothelioma. Generally, its non-specificity provides a huge challenge to medical professionals in its diagnosis, and this is also the main reason for delayed diagnosis. Patients should be vigilant, even though no clear risk factor is observed.

      Key Indexing Terms

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to The American Journal of the Medical Sciences
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Register: Create an account
      Institutional Access: Sign in to ScienceDirect

      References

        • Greenbaum A.
        • Alexander H.R.
        Peritoneal mesothelioma.
        Transl Lung Cancer Res. 2020; 9: S120-S132https://doi.org/10.21037/tlcr.2019.12.15
        View in Article
        • Noiret B.
        • Renaud F.
        • Piessen G.
        • et al.
        Multicystic peritoneal mesothelioma: a systematic review of the literature.
        Pleura Peritoneum. 2019; 4 (Published 2019 Sep 25)20190024https://doi.org/10.1515/pp-2019-0024
        View in Article
        • Alexander H.R.
        • Burke A.P.
        Diagnosis and management of patients with malignant peritoneal mesothelioma.
        J Gastrointest Oncol. 2016; 7: 79-86https://doi.org/10.3978/j.issn.2078-6891.2015.134
        View in Article
        • Li C.Y.
        • Alexander H.R.
        Peritoneal metastases from malignant mesothelioma.
        Surg Oncol Clin N Am. 2018; 27: 539-549https://doi.org/10.1016/j.soc.2018.02.010
        View in Article
        • Broeckx G.
        • Pauwels P.
        Malignant peritoneal mesothelioma: a review.
        Transl Lung Cancer Res. 2018; 7: 537-542https://doi.org/10.21037/tlcr.2018.10.04
        View in Article
        • Carbone M.
        • Adusumilli P.S.
        • Alexander H.R.
        • et al.
        Mesothelioma: scientific clues for prevention, diagnosis, and therapy [published correction appears in CA Cancer J Clin. 2020 Jul;70(4):313-314].
        CA Cancer J Clin. 2019; 69: 402-429https://doi.org/10.3322/caac.21572
        View in Article
        • Ibrahim A.M.
        • Al-Akchar M.
        • Obaidi Z.
        • et al.
        Malignant peritoneal mesothelioma: a rare cause of ascites.
        J Investig Med High Impact Case Rep. 2018; 6 (Published 2018 Oct 16)2324709618807506https://doi.org/10.1177/2324709618807506
        View in Article
        • Baker P.M.
        • Clement P.B.
        • Young R.H.
        Malignant peritoneal mesothelioma in women: a study of 75 cases with emphasis on their morphologic spectrum and differential diagnosis.
        Am J Clin Pathol. 2005; 123: 724-737https://doi.org/10.1309/2h0n-vrer-pp2l-jdua
        View in Article
        • Kim J.
        • Bhagwandin S.
        • Labow D.M.
        Malignant peritoneal mesothelioma: a review.
        Ann Transl Med. 2017; 5: 236https://doi.org/10.21037/atm.2017.03.96
        View in Article
        • Joseph N.M.
        • Chen Y.Y.
        • Nasr A.
        • et al.
        Genomic profiling of malignant peritoneal mesothelioma reveals recurrent alterations in epigenetic regulatory genes BAP1, SETD2, and DDX3X.
        Mod Pathol. 2017; 30: 246-254https://doi.org/10.1038/modpathol.2016.188
        View in Article
        • Desmeules P.
        • Joubert P.
        • Zhang L.
        • et al.
        A subset of malignant mesotheliomas in young adults are associated with recurrent EWSR1/FUS-ATF1 fusions.
        Am J Surg Pathol. 2017; 41: 980-988https://doi.org/10.1097/PAS.0000000000000864
        View in Article
        • Rodríguez D.
        • Cheung M.C.
        • Housri N.
        • et al.
        Malignant abdominal mesothelioma: defining the role of surgery.
        J Surg Oncol. 2009; 99: 51-57https://doi.org/10.1002/jso.21167
        View in Article
        • Park J.Y.
        • Kim K.W.
        • Kwon H.J.
        • et al.
        Peritoneal mesotheliomas: clinicopathologic features, CT findings, and differential diagnosis.
        AJR Am J Roentgenol. 2008; 191: 814-825https://doi.org/10.2214/AJR.07.3628
        View in Article
        • Low R.N.
        • Barone R.M.
        Combined diffusion-weighted and gadolinium-enhanced MRI can accurately predict the peritoneal cancer index preoperatively in patients being considered for cytoreductive surgical procedures.
        Ann Surg Oncol. 2012; 19: 1394-1401https://doi.org/10.1245/s10434-012-2236-3
        View in Article
        • Beebe-Dimmer J.L.
        • Fryzek J.P.
        • Yee C.L.
        • et al.
        Mesothelioma in the United States: a Surveillance, Epidemiology, and End Results (SEER)-medicare investigation of treatment patterns and overall survival.
        Clin Epidemiol. 2016; 8 (Published 2016 Oct 26): 743-750https://doi.org/10.2147/CLEP.S105396
        View in Article
        • Kobayashi M.
        • Moriwaki T.
        • Ochi D.
        • et al.
        A case of malignant peritoneal mesothelioma with the epithelioid histological type, successfully treated with pemetrexed plus cisplatin.
        Gan To Kagaku Ryoho. 2014; 41: 361-364
        View in Article

      Article info

      Publication history

      Published online: August 05, 2022
      Accepted: July 22, 2022
      Received: October 20, 2021

      Identification

      DOI: https://doi.org/10.1016/j.amjms.2022.07.008

      Copyright

      © 2022 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved.

      ScienceDirect

      Access this article on ScienceDirect
      We use cookies to help provide and enhance our service and tailor content. To update your cookie settings, please visit the for this site.
      Copyright © 2023 Elsevier Inc. except certain content provided by third parties. The content on this site is intended for healthcare professionals.


      RELX