Abstract
Background
The relationship between small pericardial effusion (SPE) and outcomes has not been
well studied in patients with heart failure. Therefore, we aimed to investigate the
prevalence and importance of SPE in acute heart failure (AHF).
Methods
A total of 398 hospitalized patients with AHF were retrospectively reviewed. Patients’
baseline demographic, clinical, echocardiographic, and laboratory characteristics
were noted. SPE was defined as the presence of a pericardial effusion <10 mm. The
primary outcome was one-year mortality.
Results
SPE was noted in 54 (13.6%) of the patients. Mortality at one year was greater for
patients with a small effusion compared with those without SPE (44.4 vs. 11.4%, respectively;
p < 0.001), and the one-year mortality rate for the whole group was 15.8%. Age (HR = 1.12,
95% CI 1.054–1.854, p = 0.024), N-terminal pro-B-type natriuretic peptide >4800 pg/ml (HR = 1.628, 95%
CI 01.102–4.805, p = 0.001), left ventricular ejection fraction <30% (HR = 1.878, 95% CI 1.154–4.524,
p = 0.001), and presence of SPE (HR = 1.567, 95% CI 1.122–2.991, p = 0.005) were independent predictors of one-year mortality on multivariate analysis.
Conclusions
The presence of SPE on admission was an independent predictor of one-year mortality
in AHF.
Keywords
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Article info
Publication history
Published online: July 21, 2022
Accepted:
June 10,
2022
Received:
June 12,
2021
Identification
Copyright
© 2022 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved.
