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Cavitary pulmonary mucormycosis caused by Cunninghamella in a patient with diabetes

      The prevalence of fungal infections is increasing along with the aggravating burden of diabetes worldwide. Candida and Aspergillus are among the most common fungal pathogens, while others are rarer and easy to be ignored such as Mucor. Pulmonary mucormycosis is a fatal opportunistic fungal infection caused by Mucor, of which Cunninghamella is reported to have the highest mortality.
      • Pomorska A
      • Malecka A
      • Jaworski R
      • et al.
      Isavuconazole in a successful combination treatment of disseminated mucormycosis in a child with acute lymphoblastic leukaemia and generalized haemochromatosis: a case report and review of the literature.
      Amphotericin B and its lipid-associated formulation are the currently recommended treatment, but it is also reported that posaconazole, a novel triazole broad-spectrum antifungal oral preparation, can be used as a combined treatment for refractory mucormycosis.
      • Carceller F
      • Oñoro G
      • Buitrago MJ
      • et al.
      Cunninghamella bertholletiae infection in children: review and report of 2 cases with disseminated infection.
      Herein, we reported a diabetic patient with pulmonary mucormycosis caused by Cunninghamella and successful treatment by posaconazole to improve awareness and share the experience of clinical diagnosis and treatment of pulmonary mucormycosis caused by Cunninghamella.
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      References

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        • Malecka A
        • Jaworski R
        • et al.
        Isavuconazole in a successful combination treatment of disseminated mucormycosis in a child with acute lymphoblastic leukaemia and generalized haemochromatosis: a case report and review of the literature.
        Mycopathologia. 2019; 184: 81-88
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        • Oñoro G
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        • et al.
        Cunninghamella bertholletiae infection in children: review and report of 2 cases with disseminated infection.
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