Abstract
Background
Epidemiologic studies suggest reduced cardiovascular disease (CVD) events with moderate
alcohol consumption. However, heavy and binge drinking may be associated with higher
CVD risk. Utilizing the Nationwide Inpatient Sample, we studied the association between
a troublesome alcohol history (TAH), defined as those with diagnoses of both chronic
alcohol syndrome and acute withdrawal history and CVD events.
Methods
Patients >18 years with diagnoses of both chronic alcohol syndrome and acute withdrawal
using the International Classification of Diseases-Ninth Edition-Clinical Modification
(ICD-9-CM) codes 303.9 and 291.81, were identified in the Nationwide Inpatient Sample
2009-2010 database. Demographics, including age and sex, as well as CVD event rates
were collected.
Results
Patients with TAH were more likely to be male, with a smoking history and have hypertension,
with less diabetes, hyperlipidemia and obesity. After multimodal adjusted regression
analysis, odds of coronary artery disease, acute coronary syndrome, in-hospital death
and heart failure were significantly lower in patients with TAH when compared to the
general discharge patient population.
Conclusions
Utilizing a large inpatient database, patients with TAH had a significantly lower
prevalence of CVD events, even after adjusting for demographic and traditional risk
factors, despite higher tobacco use and male sex predominance, when compared to the
general patient population.
Key Indexing Terms
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Article info
Publication history
Accepted:
January 18,
2018
Received in revised form:
January 9,
2018
Received:
August 7,
2017
Footnotes
☆The authors have no financial or other conflicts of interest to disclose.
Identification
Copyright
© 2018 Southern Society for Clinical Investigation. Published by All rights reserved.
