Abstract
This single-center, retrospective review identified 6 patients (n = 6, 100% female) treated by endovascular therapy for May-Thurner syndrome from June
2013 to September 2015. Patients consisted of 3 African American, 2 Caucasian and
1 Asian; mean age was 53.50 ± 8.31 years, range: 39-63 years. Clinical presentations
consisted of left lower extremity deep vein thrombosis in 4, left lower extremity
deep vein thrombosis with pulmonary embolism in 1 and pulmonary embolism with left
common iliac vein thrombosis in 1 patient. All 6 patients were treated with catheter‐directed
thrombolysis and venous stenting to correct the underlying anatomical defect. Hypercoagulability
work up revealed antiphospholipid antibody syndrome in 1 patient. No major periprocedural
complications were observed. Median follow-up period was 22 ± 5.5 months (range: 13-30
months). One patient with pre-exiting antiphospholipid antibody syndrome developed
stent thrombosis with secondary loss of patency. Endovascular therapy for May-Thurner
syndrome in our adult cohort seemed safe and effective. One patient with pre-existing
thrombophilia developed secondary loss of stent patency, suggesting need for further
investigation in this subgroup.
Key Indexing Terms
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to The American Journal of the Medical SciencesAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- The cause of the predominantly sinister occurrence of thrombosis of the pelvic veins.Angiology. 1957; 8: 419-427
- Iliac vein compression in an asymptomatic patient population.J Vasc Surg. 2004; 39: 937-943
- Antithrombotic therapy for VTE disease.Chest. 2016; 149: 315-352
- Ultrasonographic diagnosis of iliac vein compression (May-Thurner) syndrome.Diagn Interv Radiol. 2007; 13: 152-155
- Multidetector CT of vascular compression syndromes in the abdomen and pelvis.Radiographics. 2014; 34: 93-115https://doi.org/10.1148/rg.341125010
- Venous compression syndromes: clinical features, imaging findings and management.Br J Radiol. 2013; 86 (20130284)https://doi.org/10.1259/bjr.20130284
- Insufficient recanalization of thrombotic venous occlusion—risk for postthrombotic syndrome.J Vasc Interv Radiol. 2017; 28: 941-944
- Syndromes associated with the deep veins: phlegmasia cerulea dolens, May-Thurner syndrome, and nutcracker syndrome.Perspect Vasc Surg Endovasc Ther. 2010; 22: 223-230https://doi.org/10.1177/1531003511400426
- May-Thurner syndrome presenting as spontaneous left iliac vein rupture.J Vasc Surg Venous Lymphat Disord. 2016; 4: 479-481https://doi.org/10.1016/j.jvsv.2016.03.007
- Between a rock and a hard place: clinical and imaging features of vascular compression syndromes.Radiographics. 2012; 32: E33-E49https://doi.org/10.1148/rg.321115011
- The iliac compression syndrome.Br J Surg. 1965; 52: 816-821https://doi.org/10.1002/bjs.1800521028
- Prospective evaluation of endoluminal venous stents in the treatment of the May-Thurner syndrome.Ann Vasc Surg. 2002; 16: 61-64https://doi.org/10.1007/s10016-001-0143-3
- Endovascular management of acute extensive iliofemoral deep venous thrombosis caused by May-Thurner syndrome.J Vasc Interv Radiol. 2000; 11: 1297-1302https://doi.org/10.1016/S1051-0443(07)61304-9
- Iliofemoral stenting for venous occlusive disease.J Vasc Surg. 2011; 53: 706-712https://doi.org/10.1016/j.jvs.2010.09.011
- Deep venous insufficiency: the relationship between lysis and subsequent reflux.J Vasc Surg. 1993; 18 ([discussion 606-8]): 596-605https://doi.org/10.1016/0741-5214(93)90069-X
- Indications for platelet aggregation inhibitors after venous stents.Phlebology. 2013; 28: S91-S98https://doi.org/10.1177/0268355513476828
- Assessment of validity and reproducibility of a clinical scale for the post-thrombotic syndrome.Haemostasis. 1994; 24: 158
Article info
Publication history
Published online: October 17, 2017
Accepted:
September 25,
2017
Received in revised form:
September 19,
2017
Received:
March 17,
2017
Footnotes
☆The authors have no financial or other conflicts of interest to disclose.
Identification
Copyright
© 2017 Southern Society for Clinical Investigation. Published by All rights reserved.
