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Primary Hyperaldosteronism Associated with Vitiligo Vulgaris and Autoimmune Hypothyroidism

      ABSTRACT

      Type 3 polyendocrine autoimmune syndrome (PAS) is defined as the association between an autoimmune thyroid disease and 1 or more other autoimmune diseases, except for autoimmune Addison disease or hypoparathyroidism. Here we report an extremely rare case of type 3 PAS in which vitiligo vulgaris and symptomless autoimmune hypothyroidism were observed during the study of primary hyperaldosteronism.

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      References

        • Hambling C.
        • Jung R.T.
        • Browning M.C.K.
        • et al.
        Primary hyperaldosteronism-evaluation of procedures for diagnosis and localization.
        Q J Med. 1993; 86: 383-392
        • Betterle C.
        • Dal Pra C.
        • Mantero F.
        • et al.
        Autoimmune adrenal insufficiency and autoimmune polyendocrine syndromes: autoantibodies, autoantigens, and their applicability in diagnosis and disease prediction.
        Endocrine Reviews. 2002; 23: 327-364
        • Neufeld M.
        • Maclaren N.
        • Blizzard R.
        Autoimmune polyglandular syndromes.
        Pediatr Ann. 1980; 9: 154-162
        • Neufeld M.
        • Blizzard R.M.
        Polyglandular autoimmune diseases.
        in: Pinchera A. Doniach D. Fenzi G.F. Baschieri L. Symposium on autoimmune aspects on endocrine disorders. Academic Press, New York1980: 357-365
        • Neufeld M.
        • Maclaren N.K.
        • Blizzard R.
        Two types of autoimmune Addison’s disease associated with different polyglandular (PGA) syndromes.
        Medicine (Baltimore). 1981; 60: 355-362
        • Puentes F.
        • Jackson T.W.
        • Isales C.M.
        A patient with concurrent primary hyperaldosteronism and adrenal insufficiency.
        Am J Med Sci. 2004; 32886: 344-347
        • Tanaka M.
        • Izeki M.
        • Miyazaki Y.
        • et al.
        Combined primary aldosteronism and Cushing’s syndrome due to a single adrenocortical adenoma complicated by Hashimoto’s thyroiditis.
        Intern Med. 2003; 41: 911
        • Nguyen D.N.
        • Nguyen L.T.
        • Luong K.V.
        Primary aldosteronism in type 1 diabetes mellitus.
        South Med J. 2004; 97: 1138
        • Ferriss J.B.
        • Brown J.J.
        • Cumming A.M.
        • et al.
        Primary hyperparathyroidism associated with primary hyperaldosteronism.
        Acta Endocrinol (Copenh). 1983; 103: 365-370
        • Herd G.W.
        A case of primary hyperparathyroidism, primary hyperaldosteronism and Cushing’s disease.
        Acta Endocrinol (Copenh). 1984; 107: 371-374
        • Reichel H.
        • Deibert B.
        • Schmidt-Gayk H.
        • et al.
        Calcium metabolism in early chronic renal failure.
        Nephrol Dial Transplant. 1991; 6: 162-169