Abstract
The 2014 Evidence-Based Guideline for the Management of High Blood pressure in Adults
Report From the panel Members Appointed to the Eighth Joint National Committee (JNC
8) was recently published. This guideline recommended that older adults (≥60 years) without diabetes or chronic kidney disease with systolic blood pressure
(SBP) ≥150 mm Hg or diastolic blood pressure (DBP) ≥90 mm Hg be initiated on antihypertensive medication with a treatment goal SBp/DBP
<150/90 mm Hg. In contrast, the previous 3 JNC guidelines recommended treatment for
these individuals be initiated at SBP/DBP ≥140/90 mm Hg with goal SBP/DBP <140/90 mm Hg. In this article, we review randomized trials of antihypertensive medication
and observational data on SBP and DBP with cardiovascular outcomes among older adults,
possible explanations underlying the different findings from these randomized trials
and observational studies, and contemporary antihypertensive treatment patterns among
older U.S. adults. In closing, we highlight future research needs related to hypertension
and outcomes among older adults.
Key Indexing Terms
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Article info
Footnotes
The authors have no financial or other conflicts of interest to disclose.
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© 2014 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved.
